"Short term use" which looked at using Testim for 90 days at normal clinical doses show side effects like increased PSA levels, acne, hypertension and haematological changes.
An eHow article on the dangers of Testim states that "the Federal Drug Administration (FDA) warns users that some children have shown signs of early puberty when Testim is accidentally rubbed off on them. Children may grow pubic hair and behave aggressively. The FDA warns that women could develop acne or new body hair when exposed to the drug." It doesn't seem to extremely harmful affects or any indicators concerning
medical insurance The FDA lists ways to avoid this, including only applying Testim to areas covered by clothing, and by
washing with soap and water thoroughly before skin to skin contact occurs."
"Testim can aggravate problems that already exist in users with enlarged prostate glands. The National Institutes of Health noted that increased PSA (prostate-specific antigens) counts were the most common side effect seen in an hsa test group."
"Other possible dangers of Testim include swelling of the ankles, feet and other parts of the body. For patients who already suffer from kidney, heart and liver problems, this can lead to serious complications. Other concerns include swollen and painful breasts, blood clots and sleep apnea."
although these issues should obviously be monitored by yourself. It seems that simple washing with soap and water before contact should be efficient, so your wife's concerns, although valid, are easily mitigable. Good luck.