testosterone gels

testosterone gels

by Chris Steidle, MD.

The newest testosterone therapy, in gel form, can produce consistent serum testosterone levels. The hormone is absorbed into the skin, which acts as a reservoir that releases testosterone steadily into the bloodstream over a twenty-four hour period. 

Testosterone gel is a clear, colorless mixture with an alcohol and water base that dries quickly. Currently, there are two brands available, Testim and AndroGel.

Advantages of testosterone gels:

  • Once-a-day dosing
  • Normalizes testosterone levels in 24 hours
  • Convenient application sites
  • Less skin irritation than patches

Disadvantages of testosterone gels:

  • Potential for transfer to partner or child
  • More expensive than other forms of therapy

Testosterone gel products and websites: 

Product Manufacturer Dosing Administration
Testim™ Auxilium Holdings, Inc. 5-10 g per day (50 mg testosterone) Applied daily to upper arms or shoulders
AndroGel® Solvay Pharmaceuticals 5-10 g per day Applied daily to abdomen, upper arms or shoulders

  See also: FAQs about testosterone gels

References

Brawer, Michael K., MD. Androgen Supplementation and Prostate Cancer Risk: Strategies for Pretherapy Assessment and Monitoring. Rev.Urol. 2003;5 (suppl 1):S29-S33.

Caruthers, Malcolm, MD. The Testosterone Revolution. London: Thorsons; 2001.

Heaton, Jeremy, P.W., MD. Hormone Treatments and Preventive Strategies in the Aging Male: Whom and When to Treat? Rev.Urol. 2003;5(suppl 1):S16-S21.

Matsumoto, Alvin M., MD. Fundamental Aspects of Hypogonadism in the Aging Male. Rev.Urol. 2003;5(suppl 1):S3-S10.

McCulloch, Andrew, MD. Case Scenarios in Androgen Deficiency. Rev.Urol. 2003;5(suppl 1):S41-S48.

Nieschlag, E., Behre, H.M., Nieschlag, S. Testosterone: Action, Deficiency, Substitution. Berlin: 1998.

Steidle, Christopher P., MD. New Advances in the Treatment of Hypogonadism in the Aging Male. Rev.Urol. 2003;5(suppl 1):S34-S40.

Notes
1. Matsumoto, Alvin M. Fundamental Aspects of Hypogonadism in the Aging Male. Urology. Vol. 5, Supplement 1. 2003;S3-10.
2. Morley, JE. J Gend Specif Med. 2001;4:49-53.

Posted February 2004
Updated May 2009

  Next article in this series: testosterone contraindications


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