testosterone gels
by Chris Steidle, MD.
The newest testosterone therapy, in gel form, can produce consistent serum testosterone levels. The hormone is absorbed into the skin, which acts as a reservoir that releases testosterone steadily into the bloodstream over a twenty-four hour period.
Testosterone gel is a clear, colorless mixture with an alcohol and water base that dries quickly. Currently, there are two brands available, Testim and AndroGel.
Advantages of testosterone gels:
- Once-a-day dosing
- Normalizes testosterone levels in 24 hours
- Convenient application sites
- Less skin irritation than patches
Disadvantages of testosterone gels:
- Potential for transfer to partner or child
- More expensive than other forms of therapy
Testosterone gel products and websites:
| Product |
Manufacturer |
Dosing |
Administration |
| Testim™ |
Auxilium Holdings, Inc. |
5-10 g per day (50 mg testosterone) |
Applied daily to upper arms or shoulders |
| AndroGel® |
Solvay Pharmaceuticals |
5-10 g per day |
Applied daily to abdomen, upper arms or shoulders |
See also: FAQs about testosterone gels
References
Brawer, Michael K., MD. Androgen Supplementation and Prostate Cancer Risk: Strategies for Pretherapy Assessment and Monitoring. Rev.Urol. 2003;5 (suppl 1):S29-S33.
Caruthers, Malcolm, MD. The Testosterone Revolution. London: Thorsons; 2001.
Heaton, Jeremy, P.W., MD. Hormone Treatments and Preventive Strategies in the Aging Male: Whom and When to Treat? Rev.Urol. 2003;5(suppl 1):S16-S21.
Matsumoto, Alvin M., MD. Fundamental Aspects of Hypogonadism in the Aging Male. Rev.Urol. 2003;5(suppl 1):S3-S10.
McCulloch, Andrew, MD. Case Scenarios in Androgen Deficiency. Rev.Urol. 2003;5(suppl 1):S41-S48.
Nieschlag, E., Behre, H.M., Nieschlag, S. Testosterone: Action, Deficiency, Substitution. Berlin: 1998.
Steidle, Christopher P., MD. New Advances in the Treatment of Hypogonadism in the Aging Male. Rev.Urol. 2003;5(suppl 1):S34-S40.
Notes
1. Matsumoto, Alvin M. Fundamental Aspects of Hypogonadism in the Aging Male. Urology. Vol. 5, Supplement 1. 2003;S3-10.
2. Morley, JE. J Gend Specif Med. 2001;4:49-53.
Posted February 2004
Updated May 2009
Next article in this series: testosterone contraindications